Scientist II - Clinical Laboratories

For 75 years, Charles River employees have worked together to assist in the discovery, development and safe manufacture of new drug therapies. When you join our family, you will have a significant impact on the health and well-being of people across the globe. Whether your background is in life sciences, finance, IT, sales or another area, your skills will play an important role in the work we perform. In return, we’ll help you build a career that you can feel passionate about.

Job Overview

Scientist II - Clinical Laboratories

As a Scientist II for our Clinical Laboratories Scientist team at the Senneville location, you will play a key role in evaluating the potential effects of investigational drugs on platelet function, coagulation, and overall hemostatic balance using state-of-the-art in vitro and ex vivo methodologies. This position offers the opportunity to work within a multidisciplinary team of toxicologists, clinical pathologists, and translational scientists supporting both regulatory and research studies.

In this role, primary responsibilities include:

• Design, develop, validate, and conduct studies assessing drug-induced effects on hemostasis;
• Perform and interpret assays evaluating:
  • Platelet activation and physiology;
  • Platelet aggregation and secretion;
  • Platelet adhesion under flow conditions;
  • Coagulation cascade and coagulation factor activity;
  • Global hemostasis assessments.
• Develop and optimize platelet-function methodologies using:
  • Light transmission and impedance aggregometry;
  • Microfluidic and vascular-flow systems;
  • Whole blood and plasma-based assays.
• Characterize potential toxicological effects of novel therapeutics on platelet and coagulation pathways;
• Analyze, interpret, and communicate complex scientific data;
• Collaborate with multidisciplinary teams including toxicology, pathology and immunology;
• Contribute to scientific innovation, assay development, and implementation of emerging technologies in hemostasis research;
• Ensure compliance with applicable quality standards, SOPs, and regulatory requirements.

Key Elements

We are looking for the following qualifications for this role:

• Holder of a Master or a PhD in Hematology, Vascular Biology, Cell Biology, Pharmacology, Biochemistry, or a related scientific discipline;
• Strong scientific background in platelet biology, platelet physiology, and hemostasis;
• Hands-on experience with:
  • Platelet aggregation assays;
  • Microfluidic systems and flow-based thrombosis models;
  • Coagulation assays and coagulation factor testing;
• Demonstrated ability to independently design and execute experimental studies;
• Strong data analysis and scientific writing skills;
• Track record of scientific publications in relevant fields;
• Excellent verbal and written communication skills.

Role Specific Information:

• Location: 22022 route Transcanadienne, Senneville, QC, H9X 1C1;
• Transportation: We offer a shuttle service from Sainte-Anne-de-Bellevue train station and John Abbott College to the Senneville site. In addition, the site is accessible from the Anse-à-l’Orme REM station via STM bus services. Free parking. Electric vehicle charging station;
• Annual bonus based on performance;
• Schedule: Monday-Friday;
• Permanent position as of the hiring, full-time 37.5hrs per week;
• Salary: The hiring range for this position is $60 000 – $70 000 per year. Please note that salaries vary within the range based on factors including, but not limited to, experience, skills, education, certifications and location.

Why Charles River ?

• We offer competitive benefits and advantages from day one to support your well-being;
• Free gym on site;
• Employee and family assistance program;
• Excellent welcome program for new employees as well as in-house advancement and career development opportunities;
• Access to a doctor and various health professionals (telemedicine);
• 4 weeks’ Vacation & 10 Personal day policy;
• Many social activities!

If you are interested in contributing to the well-being of our communities, not only across the country but around the world, please join us. This is Your Moment

About Safety Assessment
Charles River is committed to helping our partners expedite their preclinical drug development with exceptional safety assessment services, state-of-the-art facilities and expert regulatory guidance. From individual specialty toxicology and IND enabling studies to tailored packages and total laboratory support, our deeply experienced team can design and execute programs that anticipate challenges and avoid roadblocks for a smooth, efficient journey to market. Each year approximately 300 investigational new drug (IND) programs are conducted in our Safety Assessment facilities.

About Charles River
Charles River is an early-stage contract research organization (CRO). We have built upon our foundation of laboratory animal medicine and science to develop a diverse portfolio of discovery and safety assessment services, both Good Laboratory Practice (GLP) and non-GLP, to support clients from target identification through preclinical development. Charles River also provides a suite of products and services to support our clients’ clinical laboratory testing needs and manufacturing activities. Utilizing this broad portfolio of products and services enables our clients to create a more flexible drug development model, which reduces their costs, enhances their productivity and effectiveness to increase speed to market.

With over 20,000 employees within 110 facilities in over 20 countries around the globe, we are strategically positioned to coordinate worldwide resources and apply multidisciplinary perspectives in resolving our client’s unique challenges. Our client base includes global pharmaceutical companies, biotechnology companies, government agencies and hospitals and academic institutions around the world.

At Charles River, we are passionate about our role in improving the quality of people’s lives. Our mission, our excellent science and our strong sense of purpose guide us in all that we do, and we approach each day with the knowledge that our work helps to improve the health and well-being of many across the globe. We have proudly worked on 80% of the drugs approved by the U.S. Food and Drug Administration (FDA) in the past five years.

We’re committed to providing benefits that elevate your quality of life. Based on your position these may include: bonus/incentives based on performance, 401K, paid time off, stock purchase program, Health and wellness coverage, employee and family wellbeing support programs, and work life balance flexibility.

Equal Employment Opportunity

Charles River is an equal opportunity employer and is committed to providing equal employment opportunities for all qualified applicants and employees without regard to race, color, sex, religion, national origin, ancestry, age, mental or physical disability, family status, pregnancy, military or veteran status, or any other characteristic protected by federal, state, or local laws.

It is unlawful in some states (including Massachusetts) to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.

If you are interested in applying to Charles River Laboratories and need special assistance or an accommodation due to a disability to complete any forms or to otherwise participate in the resume submission process, please contact a member of our Human Resources team by sending an e-mail message to [email protected]. This contact is for accommodation requests for individuals with disabilities only and cannot be used to inquire about the status of applications.

For more information, please visit www.criver.com.