Posted 6 months ago
Senior Scientist, Stem Cell-Derived Tissue Models( Contract)
@ Amgen British Columbia ULC
Burnaby, British Columbia
Overview
Amgen British Columbia ULC is hiring a Senior Scientist to develop and validate human stem cell-derived tissue models within its Predictive Biology team. The role involves differentiating iPSCs into tissue cell types, building organoids and co-cultures, and validating architecture and function. Salary is $115,503 to $156,269 CAD, with comprehensive Total Rewards.
Responsibilities:
- Develop stem cell-derived tissue models for disease vs normal comparisons
- Differentiate stem cells into tissue-relevant cell types
- Build organoids, assembloids and co-cultures
- Validate model architecture, maturation and function
- Document protocols and communicate results to cross-functional teams
Requirements summary:
- PhD with 2+ years experience, or MSc with 5+ years, or BSc with 8+ years
- Hands-on stem cell culture and differentiation experience
- Experience validating tissue architecture with imaging or functional assays
- Peer-reviewed publications or patents preferred
- Strong communication and collaboration skills
Tools & skills
Source and dates
Employer career site / ATS feed · workday
- Employer posting date
- 2026-05-20
- First seen by our source
- 2026-10-08
- Source record updated
- 2026-10-14
These dates describe the source record, not a live verification that the employer is still hiring. Check the original posting.
Job details
| Seniority | Senior |
| Department | Research & science |
| Experience | 2+ years |
| Hours per week | 40 (estimated) |
| Work setting | Laboratory |
| Position | Sitting and standing |
| Physical demands | physical low · computer moderate |
| Languages | English |
| Education | Doctorate (preferred), Master’s degree (required), Bachelor’s degree (required) |
| Fields of study | stem cell biology, developmental biology, tissue engineering, cell biology, bioengineering |
Summary and details written by AI from the posting; the employer’s posting is the authority.
Amgen British Columbia ULC
| Field | Value |
|---|---|
| Open jobs on Jobsy | 7 |
Career Category
ScientificJob Description
Join Amgen’s Mission of Serving Patients
At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do.
Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas –Oncology, Inflammation, General Medicine, and Rare Disease– we reach millions of patients each year. Amgen is advancing a broad and deep pipeline of medicines to treat cancer, heart disease, inflammatory conditions, rare diseases, and obesity and obesity-related conditions. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.
Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.
What you will do
Let’s do this. Let’s change the world. In this vital role, you will join the Predictive Biology team to develop and validate biologically relevant models of human tissue using induced pluripotent stem cell (iPSC) or primary human tissue. A key focus will be validating tissue architecture, cellular composition, differentiation state, maturation, and functional relevance to ensure models are suitable for discovery and translational research.
Key Responsibilities
- Develop human stem cell-derived models that represent tissue biology and enable disease-versus-normal comparisons.
- Differentiate stem cells into diverse tissue-relevant cell types.
- Build complex model systems, including organoids, assembloids, co-cultures, matrix-supported cultures, or other multicellular tissue-like systems.
- Optimize culture conditions, media composition, growth factor cues, extracellular matrix conditions, differentiation timing, and co-culture parameters.
- Validate model fidelity using readouts of cell identity, tissue architecture, maturation, and tissue-specific function.
- Document protocols, experimental designs, model validation data, and decision criteria in a clear and reproducible manner.
- Communicate results, limitations, and technical risks to cross-functional teams through written reports and oral presentations.
What we expect of you
We are all different, yet we all use our unique contributions to serve patients. The Senior Scientist we seek is a professional with these qualifications.
Basic Qualifications
- PhD in a related discipline with 2+ years of experience
- MSc with 5+ years of experience.
- BSc with 8+ years of experience.
Preferred Qualifications
- PhD with 2+ years postdoctoral and/or industry experience in stem cell biology, developmental biology, tissue engineering, cell biology, bioengineering, molecular biology, organoid biology, or a related discipline.
- Hands-on experience culturing and differentiating stem cells across relevant model systems
- Experience validating tissue architecture using methods such as immunostaining, confocal microscopy, flow cytometry, high-content imaging, or functional assays.
- Experience optimizing media, growth factors, extracellular matrix conditions, differentiation timing, and co-culture conditions for multicellular model systems.
- Familiarity with adult stem cell-derived organoids, Lgr5-positive stem cell biology, niche-factor-dependent epithelial systems, normal organoids, or patient-derived organoid platforms is preferred but not required.
- Demonstrated scientific productivity and technical credibility through peer-reviewed publications and patents
- Strong communication and collaboration skills and ability to work effectively as part of a multidisciplinary team.
What you can expect of us
As we work to develop treatments that take care of others, we also work to care for our teammates’ professional and personal growth and well-being.
Amgen is proud to have been recognized as one of LinkedIn Top 25 Companies in Canada for career growth. Click HERE for more details.
The salary range for this position in Canada is $115,503 - $156,269 CAD.
In addition to the base salary, Amgen offers competitive and comprehensive Total Rewards Plans that are aligned with local industry standards.
Apply now and make a lasting impact with the Amgen team.
careers.amgen.com
As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease.
Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law.
We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.
.Salary Range
115,503.10 CAD - 156,268.90 CADJournal
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